Cancer and Fertility Preservations

A cancer diagnosis may not immediately lead to thoughts about preserving one’s fertility. But, if you’re a woman of childbearing age or a man who is concerned about his future ability to become a father, it is important to understand that the treatments that help fight cancer may also affect your ability to have children.

Fortunately, there are more options to preserve your fertility than ever before.


Different cancer treatments affect the body in different ways. Chemotherapy, radiation and surgery can all affect your reproductive system. In general, the higher the dose and longer the treatment, the higher the chance for reproductive problems. Ask your doctor to help determine the fertility risks associated with your individual treatment regimen.

Men: Sperm Freezing: Sperm may be frozen and “banked” for future use. It is strongly recommended that sperm be collected prior to initiation of treatment because the quality of the sample and sperm DNA integrity may be compromised even after a single treatment session. Even if your Sperm Count is low or you only have time to make one deposit, Sperm Banking may still be worthwhile. Once sperm is frozen, there is no set time limit as to how long it can remain frozen until it is used. Testicular Tissue Freezing is an option for some men who cannot bank sperm because of the inability to ejaculate. When sperm are present in the testicle but not in the semen, it is a relatively straight-forward outpatient surgical procedure to remove sperm-bearing tissue from the testicles and freeze it for future use.

Women: Egg Freezing: Egg freezing is now a very good option for unmarried women. At Rotunda, we have an excellent Egg Vitrification Program and our pregnancy rates after egg freezing are comparable to fresh eggs. The process requires hormonal stimulation to retrieve your eggs and takes two to six weeks.

Embryo Freezing: Embryo freezing is a proven, successful way to try to preserve your fertility. It is a good option to consider if you are married, have a committed partner or are willing to use donor sperm. The process requires hormonal stimulation to retrieve your eggs.

Ovarian Tisssue Freezing: Ovarian tissue freezing may be a good option if you do not have a lot of time before treatment or if you cannot have the hormonal stimulation needed for egg retrieval and either Egg or Embryo Freezing. This approach involves the surgical removal and freezing of ovarian tissue.

Men: It is ideal to bank sperms before treatment. But, if you have not been able to do that, and if you are still producing sperms after treatment, you should talk to your doctor about how long you should wait for sperm banking after radiation or chemotherapy.

Women: Egg Freezing, Embryo Freezing and Ovarian Tissue Freezing are usually thought of as pre-treatment options. They can also be done after cancer treatment. If you are fertile, but worried that you might go into early menopause before you are ready to start a family, you may want to preserve your fertility after treatment.

Men: A Semen Analysis is a simple test that can be performed after you finish treatment.

Women: If you are having periods without the aid of hormonal supplements like birth control pills, you may still be fertile. Simple hormone tests and ultrasound can be used to check your fertility.

Men: Natural conception can occur if your semen analysis is in the normal range. If you have banked sperm, it can be used in In Vitro Fertilization (IVF) to impregnate your wife or partner.

Women: Natural conception may be possible if you remain fertile after treatment. If you have undergone Egg, Embryo or Ovarian Tissue Freezing, you can use this genetic material and get pregnant with the help of IVF.

Many cancer survivors have children after treatment.

Currently available studies suggest that pregnancy after cancer does not reduce chances of the patient’s survival. It does not trigger cancer recurrence, even after breast cancer.

Radiation to the uterus can increase the risk of miscarriage or premature births.

Sperm cells exposed to chemotherapy or radiation may suffer genetic damage. This damage appears to be repaired one to two years after treatment.

Rates of birth defects in the general population are 2% to 3%. Rates of birth defects in children born after one parent’s cancer treatment appear similar; no higher than 6% and probably less. No unusual cancer risk has been identified in the offspring of cancer survivors (except in families identified with true genetic cancer syndromes, for example, Inherited Retinoblastoma).

Many options exist for you to become a parent. Thinking about fertility now can help assure you have choices when you are ready to become a parent. Talk to your medical team about your treatment and its effects on your fertility. Our team of Fertility Physicians and Embryologists will be happy to work with you and your doctor to assist you in preserving your fertility.